Dinucleoside polyphosphates act as 5′-RNA caps in bacteria

It has been more than 50 years since the discovery of dinucleoside polyphosphates (Np(n)Ns) and yet their roles and mechanisms of action remain unclear. Here, we show that both methylated and non-methylated Np(n)Ns serve as RNA caps in Escherichia coli. Np(n)Ns are excellent substrates for T7 and E....

Descripción completa

Detalles Bibliográficos
Autores principales: Hudeček, Oldřich, Benoni, Roberto, Reyes-Gutierrez, Paul E., Culka, Martin, Šanderová, Hana, Hubálek, Martin, Rulíšek, Lubomír, Cvačka, Josef, Krásný, Libor, Cahová, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044304/
https://www.ncbi.nlm.nih.gov/pubmed/32103016
http://dx.doi.org/10.1038/s41467-020-14896-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044304/
https://www.ncbi.nlm.nih.gov/pubmed/32103016
http://dx.doi.org/10.1038/s41467-020-14896-8

Ejemplares similares