Systematic comparison of somatic variant calling performance among different sequencing depth and mutation frequency

In the past decade, treatments for tumors have made remarkable progress, such as the successful clinical application of targeted therapies. Nowadays, targeted therapies are based primarily on the detection of mutations, and next-generation sequencing (NGS) plays an important role in relevant clinica...

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Detalles Bibliográficos
Autores principales: Chen, Zixi, Yuan, Yuchen, Chen, Xiaoshi, Chen, Jiayun, Lin, Shudai, Li, Xingsong, Du, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044309/
https://www.ncbi.nlm.nih.gov/pubmed/32103116
http://dx.doi.org/10.1038/s41598-020-60559-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044309/
https://www.ncbi.nlm.nih.gov/pubmed/32103116
http://dx.doi.org/10.1038/s41598-020-60559-5

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