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Systematic comparison of somatic variant calling performance among different sequencing depth and mutation frequency
In the past decade, treatments for tumors have made remarkable progress, such as the successful clinical application of targeted therapies. Nowadays, targeted therapies are based primarily on the detection of mutations, and next-generation sequencing (NGS) plays an important role in relevant clinica...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044309/ https://www.ncbi.nlm.nih.gov/pubmed/32103116 http://dx.doi.org/10.1038/s41598-020-60559-5 |