Spatial modeling of prostate cancer metabolic gene expression reveals extensive heterogeneity and selective vulnerabilities

Spatial heterogeneity is a fundamental feature of the tumor microenvironment (TME), and tackling spatial heterogeneity in neoplastic metabolic aberrations is critical for tumor treatment. Genome-scale metabolic network models have been used successfully to simulate cancer metabolic networks. However...

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Detalles Bibliográficos
Autores principales: Wang, Yuliang, Ma, Shuyi, Ruzzo, Walter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044328/
https://www.ncbi.nlm.nih.gov/pubmed/32103057
http://dx.doi.org/10.1038/s41598-020-60384-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044328/
https://www.ncbi.nlm.nih.gov/pubmed/32103057
http://dx.doi.org/10.1038/s41598-020-60384-w

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