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Streptonigrin at low concentration promotes heterochromatin formation

Heterochromatin is essential for regulating global gene transcription and protecting genome stability, and may play a role in tumor suppression. Drugs promoting heterochromatin are potential cancer therapeutics but very few are known. In order to identify drugs that can promote heterochromatin, we u...

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Detalles Bibliográficos
Autores principales: Loyola, Andre C., Dao, Kevin, Shang, Robin, Zhang, Lin, Dutta, Pranabananda, Fowler, Cody, Li, Jinghong, Li, Willis X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044429/
https://www.ncbi.nlm.nih.gov/pubmed/32103104
http://dx.doi.org/10.1038/s41598-020-60469-6