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FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling

FAM172A, as a newly discovered gene, is little known in cancer development, especially in pancreatic cancer (PC). We investigated the potential role and molecular mechanism of FAM172A in epithelial to mesenchymal transition (EMT) in both human clinical samples and PC cells. FAM172A was downregulated...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Liu, Peihui, Shen, Di, Liu, Han, Xu, Lepeng, Wang, Jian, Shen, Daguang, Sun, He, Wu, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044457/
https://www.ncbi.nlm.nih.gov/pubmed/31988090
http://dx.doi.org/10.1242/bio.048462