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A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza

Immunogenicity of DNA vaccines can be increased by constructing the DNA in such a way that it encodes secreted homodimeric fusion proteins that target antigen-presenting cells (APCs). In this study, we have developed novel APC-targeting vaccine molecules with an increased flexibility due to introduc...

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Detalles Bibliográficos
Autores principales: Braathen, Ranveig, Spång, Heidi Cecilie Larsen, Hinke, Daniëla Maria, Blazevski, Jana, Bobic, Sonja, Fossum, Even, Bogen, Bjarne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044496/
https://www.ncbi.nlm.nih.gov/pubmed/32128342
http://dx.doi.org/10.1016/j.omtm.2020.01.007