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The Identification of Long Non-coding RNA H19 Target and Its Function in Chronic Myeloid Leukemia

H19 is a long non-coding RNA which was lowly expressed in chronic myeloid leukemia (CML). Here, we found that the overexpression of H19 significantly inhibited cell viability and colony formation and prolongs survival in CML cell lines and three xenografted mouse models. The H19 target proteins and...

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Detalles Bibliográficos
Autores principales: Yang, Juhua, Yin, Zhao, Li, Yumin, Liu, Yanjun, Huang, Guiping, Gu, Chunming, Fei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044501/
https://www.ncbi.nlm.nih.gov/pubmed/32160707
http://dx.doi.org/10.1016/j.omtn.2020.01.021