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Rapid Delivery of Nanobodies/V(H)Hs into Living Cells via Expressing In Vitro-Transcribed mRNA

Intracellular antigen labeling and manipulation by antibodies have been long-thought goals in the field of cell research and therapy. However, a central limitation for this application is that antibodies are not able to penetrate into the cytosol of living cells. Taking advantages of small sizes and...

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Detalles Bibliográficos
Autores principales: Zhou, Xuechen, Hao, Rui, Chen, Chen, Su, Zhipeng, Zhao, Linhong, Luo, Zhuojuan, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044678/
https://www.ncbi.nlm.nih.gov/pubmed/32128345
http://dx.doi.org/10.1016/j.omtm.2020.01.008