Assessment of the stability of citrate-buffered flucloxacillin for injection when stored in two commercially available ambulatory elastomeric devices: INfusor LV (Baxter) and Accufuser (Woo Young Medical): a study compliant with the NHS Yellow Cover Document (YCD) requirements

OBJECTIVES: To investigate the effect of pH and buffers on the degradation rate of flucloxacillin and to determine if flucloxacillin can be stabilised using a buffered diluent for up to 14 days when stored at 2°C–8°C including a 24-hour infusion period at 32°C in two elastomeric devices (Accufuser a...

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Detalles Bibliográficos
Autores principales: Allwood, Michael Charles, Stonkute, Donata, Wallace, Andrew, Wilkinson, Alan-Shaun, Hills, Tim, Jamieson, Conor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044701/
https://www.ncbi.nlm.nih.gov/pubmed/32153771
http://dx.doi.org/10.1136/ejhpharm-2018-001515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044701/
https://www.ncbi.nlm.nih.gov/pubmed/32153771
http://dx.doi.org/10.1136/ejhpharm-2018-001515

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