Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome

During adult hippocampal neurogenesis, most newborn cells undergo apoptosis and are rapidly phagocytosed by resident microglia to prevent the spillover of intracellular contents. Here, we propose that phagocytosis is not merely passive corpse removal but has an active role in maintaining neurogenesi...

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Detalles Bibliográficos
Autores principales: Diaz-Aparicio, Irune, Paris, Iñaki, Sierra-Torre, Virginia, Plaza-Zabala, Ainhoa, Rodríguez-Iglesias, Noelia, Márquez-Ropero, Mar, Beccari, Sol, Huguet, Paloma, Abiega, Oihane, Alberdi, Elena, Matute, Carlos, Bernales, Irantzu, Schulz, Angela, Otrokocsi, Lilla, Sperlagh, Beata, Happonen, Kaisa E., Lemke, Greg, Maletic-Savatic, Mirjana, Valero, Jorge, Sierra, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044727/
https://www.ncbi.nlm.nih.gov/pubmed/31896673
http://dx.doi.org/10.1523/JNEUROSCI.0993-19.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044727/
https://www.ncbi.nlm.nih.gov/pubmed/31896673
http://dx.doi.org/10.1523/JNEUROSCI.0993-19.2019

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