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Computational modeling of the effects of autophagy on amyloid-β peptide levels
BACKGROUND: Autophagy is an evolutionarily conserved intracellular process that is used for delivering proteins and organelles to the lysosome for degradation. For decades, autophagy has been speculated to regulate amyloid-β peptide (Aβ) accumulation, which is involved in Alzheimer’s disease (AD); h...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045373/ https://www.ncbi.nlm.nih.gov/pubmed/32102666 http://dx.doi.org/10.1186/s12976-020-00119-6 |