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Computational modeling of the effects of autophagy on amyloid-β peptide levels

BACKGROUND: Autophagy is an evolutionarily conserved intracellular process that is used for delivering proteins and organelles to the lysosome for degradation. For decades, autophagy has been speculated to regulate amyloid-β peptide (Aβ) accumulation, which is involved in Alzheimer’s disease (AD); h...

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Detalles Bibliográficos
Autores principales:	Han, Kyungreem, Kim, Soon Ho, Choi, MooYoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045373/ https://www.ncbi.nlm.nih.gov/pubmed/32102666 http://dx.doi.org/10.1186/s12976-020-00119-6

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