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Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84

BACKGROUND: Medium-chain fatty acids and their 3-hydroxy derivatives are metabolites endogenously produced in humans, food-derived or originating from bacteria. They activate G protein-coupled receptors, including GPR84 and HCA(3), which regulate metabolism and immune functions. Although both recept...

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Detalles Bibliográficos
Autores principales: Peters, Anna, Rabe, Philipp, Krumbholz, Petra, Kalwa, Hermann, Kraft, Robert, Schöneberg, Torsten, Stäubert, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045412/
https://www.ncbi.nlm.nih.gov/pubmed/32102673
http://dx.doi.org/10.1186/s12964-020-0516-2