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Natural polymorphisms in HIV-1 CRF01_AE strain and profile of acquired drug resistance mutations in a long-term combination treatment cohort in northeastern China

BACKGROUND: The impacts of genetic polymorphisms on drug resistance mutations (DRMs) among various HIV-1 subtypes have long been debated. In this study, we aimed to analyze the natural polymorphisms and acquired DRM profile in HIV-1 CRF01_AE-infected patients in a large first-line antiretroviral the...

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Detalles Bibliográficos
Autores principales: Sun, Zesong, Ouyang, Jinming, Zhao, Bin, An, Minghui, Wang, Lin, Ding, Haibo, Han, Xiaoxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045473/
https://www.ncbi.nlm.nih.gov/pubmed/32102660
http://dx.doi.org/10.1186/s12879-020-4808-3