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Natural polymorphisms in HIV-1 CRF01_AE strain and profile of acquired drug resistance mutations in a long-term combination treatment cohort in northeastern China
BACKGROUND: The impacts of genetic polymorphisms on drug resistance mutations (DRMs) among various HIV-1 subtypes have long been debated. In this study, we aimed to analyze the natural polymorphisms and acquired DRM profile in HIV-1 CRF01_AE-infected patients in a large first-line antiretroviral the...
Autores principales: | Sun, Zesong, Ouyang, Jinming, Zhao, Bin, An, Minghui, Wang, Lin, Ding, Haibo, Han, Xiaoxu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045473/ https://www.ncbi.nlm.nih.gov/pubmed/32102660 http://dx.doi.org/10.1186/s12879-020-4808-3 |
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