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Characterization of novel LncRNA P14AS as a protector of ANRIL through AUF1 binding in human cells

BACKGROUND: The CDKN2A/B locus contains crucial tumor suppressors and a lncRNA gene ANRIL. However, the mechanisms that coordinately regulate their expression levels are not clear. METHODS: Novel RNAs transcribed from the CDKN2A gene were screened by CDKN2A-specific RNA capture deep-sequencing and c...

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Detalles Bibliográficos
Autores principales: Ma, Wanru, Qiao, Juanli, Zhou, Jing, Gu, Liankun, Deng, Dajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045492/
https://www.ncbi.nlm.nih.gov/pubmed/32106863
http://dx.doi.org/10.1186/s12943-020-01150-4