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DMN-Tre Labeling for Detection and High-Content Screening of Compounds against Intracellular Mycobacteria
[Image: see text] 4-N,N-Dimethylamino-1,8-naphthalimide conjugate of trehalose (DMN-Tre) is a fluorogenic dye recently developed as a diagnostic tool for tuberculosis. DMN-Tre selectively labels the mycobacterial cell wall through the Ag85 enzymes. In this work, we disclose a protocol describing the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045496/ https://www.ncbi.nlm.nih.gov/pubmed/32118181 http://dx.doi.org/10.1021/acsomega.9b04173 |