Improved Synthesis and Isolation of Bedaquiline

[Image: see text] Bedaquiline (BDQ) is the most critical pharmaceutical in the world for treating multidrug-resistant Mycobacterium tuberculosis. Despite it being highly effective, BDQ asymmetric synthesis remains a challenge. Herein, the influence of chiral bases, namely, bis(1-phenylethyl)amine, b...

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Detalles Bibliográficos
Autores principales: Lubanyana, Hlengekile, Arvidsson, Per I., Govender, Thavendran, Kruger, Hendrik G., Naicker, Tricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045498/
https://www.ncbi.nlm.nih.gov/pubmed/32118176
http://dx.doi.org/10.1021/acsomega.9b04037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045498/
https://www.ncbi.nlm.nih.gov/pubmed/32118176
http://dx.doi.org/10.1021/acsomega.9b04037

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