Ortho versus Meta Chlorophenyl-2,3-Benzodiazepine Analogues: Synthesis, Molecular Modeling, and Biological Activity as AMPAR Antagonists

[Image: see text] 2,3-Benzodiazepine compounds are an important family of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) antagonists that act in a noncompetitive manner. Due to the critical role of AMPARs in the synapse and various neurological diseases, significant scientific...

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Detalles Bibliográficos
Autores principales: Qneibi, Mohammad, Jaradat, Nidal, Hawash, Mohammed, Olgac, Abdurrahman, Emwas, Nour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045501/
https://www.ncbi.nlm.nih.gov/pubmed/32118174
http://dx.doi.org/10.1021/acsomega.9b04000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045501/
https://www.ncbi.nlm.nih.gov/pubmed/32118174
http://dx.doi.org/10.1021/acsomega.9b04000

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