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Large-scale public data reuse to model immunotherapy response and resistance

Despite growing numbers of immune checkpoint blockade (ICB) trials with available omics data, it remains challenging to evaluate the robustness of ICB response and immune evasion mechanisms comprehensively. To address these challenges, we integrated large-scale omics data and biomarkers on published...

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Detalles Bibliográficos
Autores principales: Fu, Jingxin, Li, Karen, Zhang, Wubing, Wan, Changxin, Zhang, Jing, Jiang, Peng, Liu, X. Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045518/
https://www.ncbi.nlm.nih.gov/pubmed/32102694
http://dx.doi.org/10.1186/s13073-020-0721-z