Enantioselective Aldol Addition of Acetaldehyde to Aromatic Aldehydes Catalyzed by Proline-Based Carboligases

[Image: see text] Aromatic β-hydroxyaldehydes, 1,3-diols, and α,β-unsaturated aldehydes are valuable precursors to biologically active natural products and drug molecules. Herein we report the biocatalytic aldol condensation of acetaldehyde with various aromatic aldehydes to give a number of aromati...

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Detalles Bibliográficos
Autores principales: Saifuddin, Mohammad, Guo, Chao, Biewenga, Lieuwe, Saravanan, Thangavelu, Charnock, Simon J., Poelarends, Gerrit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045556/
https://www.ncbi.nlm.nih.gov/pubmed/32117575
http://dx.doi.org/10.1021/acscatal.0c00039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045556/
https://www.ncbi.nlm.nih.gov/pubmed/32117575
http://dx.doi.org/10.1021/acscatal.0c00039

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