Cargando…
Post-SELEX Optimization and Characterization of a Prostate Cancer Cell-Specific Aptamer for Diagnosis
[Image: see text] The RNA aptamer A4 binds specifically to tumor prostate cells. A4 was modified (mA4) by adding deoxyribonucleotides to its ends to remove the reactive 2′ hydroxyl groups of RNA’s sugar at the ends of the aptamer and to make it more stable to widespread RNase contamination in labora...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045564/ https://www.ncbi.nlm.nih.gov/pubmed/32118168 http://dx.doi.org/10.1021/acsomega.9b03855 |