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A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites

Malaria parasites rely on a plastid organelle for survival during the blood stages of infection. However, the entire organelle is dispensable as long as the isoprenoid precursor, isopentenyl pyrophosphate (IPP), is supplemented in the culture medium. We engineered parasites to produce isoprenoid pre...

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Detalles Bibliográficos
Autores principales: Swift, Russell P., Rajaram, Krithika, Liu, Hans B., Dziedzic, Amanda, Jedlicka, Anne E., Roberts, Aleah D., Matthews, Krista A., Jhun, Hugo, Bumpus, Namandje N., Tewari, Shivendra G., Wallqvist, Anders, Prigge, Sean T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046295/
https://www.ncbi.nlm.nih.gov/pubmed/32059044
http://dx.doi.org/10.1371/journal.ppat.1008316