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IGFBP7 acts as a negative regulator of RANKL‐induced osteoclastogenesis and oestrogen deficiency‐induced bone loss

OBJECTIVES: Insulin‐like growth factor‐binding protein 7 (IGFBP7) is a low‐affinity insulin growth factor (IGF) binder that may play an important role in bone metabolism. We previously reported that IGFBP7 enhanced osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (BMSCs) via...

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Detalles Bibliográficos
Autores principales: Ye, Chenyi, Hou, Weiduo, Chen, Mo, Lu, Jinwei, Chen, Erman, Tang, Lan, Hang, Kai, Ding, Qianhai, Li, Yan, Zhang, Wei, He, Rongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046308/
https://www.ncbi.nlm.nih.gov/pubmed/31889368
http://dx.doi.org/10.1111/cpr.12752