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Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

Detecting relative rather than absolute changes in extracellular signals enables cells to make decisions in constantly fluctuating environments. It is currently not well understood how mammalian signaling networks store the memories of past stimuli and subsequently use them to compute relative signa...

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Detalles Bibliográficos
Autores principales: Lyashenko, Eugenia, Niepel, Mario, Dixit, Purushottam D, Lim, Sang Kyun, Sorger, Peter K, Vitkup, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046471/
https://www.ncbi.nlm.nih.gov/pubmed/31961323
http://dx.doi.org/10.7554/eLife.50342