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Click Inspired Synthesis of Novel Cinchonidine Glycoconjugates as Promising Plasmepsin Inhibitors

Among all the malaria parasites, P. falciparum is the most predominant species which has developed drug resistance against most of the commercial anti-malarial drugs. Thus, finding a new molecule for the inhibition of enzymes of P. falciparum is the pharmacological challenge in present era. Herein,...

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Detalles Bibliográficos
Autores principales: Mishra, Nidhi, Agrahari, Anand K., Bose, Priyanka, Singh, Sumit K., Singh, Anoop S., Tiwari, Vinod K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046651/
https://www.ncbi.nlm.nih.gov/pubmed/32108142
http://dx.doi.org/10.1038/s41598-020-59477-3