Hyperprogression under Immune Checkpoint Inhibitor: a potential role for germinal immunogenetics

Hyperprogressive disease (HPD), an unexpected acceleration of tumor growth kinetics, is described in cancer patients treated with anti-PD-1/anti-PD-L1 agents. Here, our aim was to take into consideration the host and explore whether single nucleotide polymorphisms (SNPs) in key genes involved in imm...

Descripción completa

Detalles Bibliográficos
Autores principales: Refae, Sadal, Gal, Jocelyn, Brest, Patrick, Giacchero, Damien, Borchiellini, Delphine, Ebran, Nathalie, Peyrade, Frederic, Guigay, Joël, Milano, Gérard, Saada-Bouzid, Esma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046673/
https://www.ncbi.nlm.nih.gov/pubmed/32107407
http://dx.doi.org/10.1038/s41598-020-60437-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046673/
https://www.ncbi.nlm.nih.gov/pubmed/32107407
http://dx.doi.org/10.1038/s41598-020-60437-0

Ejemplares similares