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Increased Lung Catalase Activity Confers Protection Against Experimental RSV Infection

Respiratory syncytial virus (RSV) infection in mouse and human lung is associated with oxidative injury and pathogenic inflammation. RSV impairs antioxidant responses by increasing the degradation of transcription factor NRF2, which controls the expression of several antioxidant enzyme (AOE) genes,...

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Detalles Bibliográficos
Autores principales: Ansar, Maria, Ivanciuc, Teodora, Garofalo, Roberto P., Casola, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046725/
https://www.ncbi.nlm.nih.gov/pubmed/32107411
http://dx.doi.org/10.1038/s41598-020-60443-2