Immobilization of Cofactor Self-Sufficient Recombinant Escherichia coli for Enantioselective Biosynthesis of (R)-1-Phenyl-1,2-Ethanediol

(R)-1-phenyl-1,2-ethanediol is an important synthon for the preparation of β-adrenergic blocking agents. This study identified a (2R,3R)-butanediol dehydrogenase (KgBDH) from Kurthia gibsonii SC0312, which showed high enantioselectivity for production of (R)-1-phenyl-1,2-ethanediol by reduction of 2...

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Detalles Bibliográficos
Autores principales: Peng, Fei, Su, Hui-Hui, Ou, Xiao-Yang, Ni, Zi-Fu, Zong, Min-Hua, Lou, Wen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046757/
https://www.ncbi.nlm.nih.gov/pubmed/32154222
http://dx.doi.org/10.3389/fbioe.2020.00017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046757/
https://www.ncbi.nlm.nih.gov/pubmed/32154222
http://dx.doi.org/10.3389/fbioe.2020.00017

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