Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation

Parkinson’s Disease is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta, the extracellular accumulation of toxic α-synuclein (αSYN) aggregates, and neuroinflammation. Microglia, resident macrophages of the brain, are one of the critical cell types involved in n...

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Detalles Bibliográficos
Autores principales: Zhao, Nanxia, Yang, Xue, Calvelli, Hannah R., Cao, Yue, Francis, Nicola L., Chmielowski, Rebecca A., Joseph, Laurie B., Pang, Zhiping P., Uhrich, Kathryn E., Baum, Jean, Moghe, Prabhas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046761/
https://www.ncbi.nlm.nih.gov/pubmed/32154238
http://dx.doi.org/10.3389/fbioe.2020.00112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046761/
https://www.ncbi.nlm.nih.gov/pubmed/32154238
http://dx.doi.org/10.3389/fbioe.2020.00112

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