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Integrated metabolome analysis reveals novel connections between maternal fecal metabolome and the neonatal blood metabolome in women with gestational diabetes mellitus

Gestational Diabetes Mellitus (GDM), which is correlated with changes in the gut microbiota, is a risk factor for neonatal inborn errors of metabolism (IEMs). Maternal hyperglycemia exerts epigenetic effects on genes that encode IEM-associated enzymes, resulting in changes in the neonatal blood meta...

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Detalles Bibliográficos
Autores principales: Zhao, Chunchao, Ge, Jun, Li, Xia, Jiao, Ruifen, Li, Yuan, Quan, Huili, Li, Jianguo, Guo, Qing, Wang, Wenju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046769/
https://www.ncbi.nlm.nih.gov/pubmed/32107447
http://dx.doi.org/10.1038/s41598-020-60540-2