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Intracranial glioma xenograft model rapidly reestablishes blood–brain barrier integrity for longitudinal imaging of tumor progression using fluorescence molecular tomography and contrast agents

Significance: The blood–brain barrier (BBB) is a major obstacle to detecting and treating brain tumors. Overcoming this challenge will facilitate the early and accurate detection of brain lesions and guide surgical resection of tumors. Aim: We generated an orthotopic brain tumor model that simulates...

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Detalles Bibliográficos
Autores principales: Habimana-Griffin, LeMoyne, Ye, Dezhuang, Carpenter, Julia, Prior, Julie, Sudlow, Gail, Marsala, Lynne, Mixdorf, Matthew, Rubin, Joshua B., Chen, Hong, Achilefu, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047009/
https://www.ncbi.nlm.nih.gov/pubmed/32112540
http://dx.doi.org/10.1117/1.JBO.25.2.026004