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PARP inhibitor-induced torsades de pointes in long QT syndrome: a case report
BACKGROUND: Poly ADP-ribose polymerase (PARP) inhibitors target pathogenic BRCA mutations in chemotherapy-resistant malignancies. PARP inhibitors cause modest dose-dependent QT prolongation in the setting of a normal baseline QT interval. CASE SUMMARY: We describe a case of PARP inhibitor-induced to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047052/ https://www.ncbi.nlm.nih.gov/pubmed/32128485 http://dx.doi.org/10.1093/ehjcr/ytz230 |