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PARP inhibitor-induced torsades de pointes in long QT syndrome: a case report

BACKGROUND: Poly ADP-ribose polymerase (PARP) inhibitors target pathogenic BRCA mutations in chemotherapy-resistant malignancies. PARP inhibitors cause modest dose-dependent QT prolongation in the setting of a normal baseline QT interval. CASE SUMMARY: We describe a case of PARP inhibitor-induced to...

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Detalles Bibliográficos
Autores principales:	Segan, Louise, Beekman, Ashley, Parfrey, Shane, Perrin, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Case Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047052/ https://www.ncbi.nlm.nih.gov/pubmed/32128485 http://dx.doi.org/10.1093/ehjcr/ytz230

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