Use of LUCS (Light-Up Cell System) as an alternative live cell method to predict human acute oral toxicity

LUCS (Light-Up Cell System) is a new live cell test that allows assessment of a cell’s homeostasis and its alteration by a toxic agent. To evaluate the effectiveness of LUCS as an alternative test method for acute oral toxicity, we compared EC(50)s determined in HepG2 cells treated with 53 chemicals...

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Detalles Bibliográficos
Autores principales: Gironde, C., Dufour, C., Furger, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047139/
https://www.ncbi.nlm.nih.gov/pubmed/32140424
http://dx.doi.org/10.1016/j.toxrep.2020.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047139/
https://www.ncbi.nlm.nih.gov/pubmed/32140424
http://dx.doi.org/10.1016/j.toxrep.2020.02.010

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