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Use of LUCS (Light-Up Cell System) as an alternative live cell method to predict human acute oral toxicity
LUCS (Light-Up Cell System) is a new live cell test that allows assessment of a cell’s homeostasis and its alteration by a toxic agent. To evaluate the effectiveness of LUCS as an alternative test method for acute oral toxicity, we compared EC(50)s determined in HepG2 cells treated with 53 chemicals...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047139/ https://www.ncbi.nlm.nih.gov/pubmed/32140424 http://dx.doi.org/10.1016/j.toxrep.2020.02.010 |