Neuron-specific knockdown of solute carrier protein SLC25A46a induces locomotive defects, an abnormal neuron terminal morphology, learning disability, and shortened lifespan

Various mutations in the SLC25A46 gene have been reported in mitochondrial diseases that are sometimes classified as type 2 Charcot-Marie-Tooth disease, optic atrophy, and Leigh syndrome. Although human SLC25A46 is a well-known transporter that acts through the mitochondrial outer membrane, the rela...

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Detalles Bibliográficos
Autores principales: Ali, Md Saheb, Suda, Kojiro, Kowada, Ryosuke, Ueoka, Ibuki, Yoshida, Hideki, Yamaguchi, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047145/
https://www.ncbi.nlm.nih.gov/pubmed/32140609
http://dx.doi.org/10.1016/j.ibror.2020.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047145/
https://www.ncbi.nlm.nih.gov/pubmed/32140609
http://dx.doi.org/10.1016/j.ibror.2020.02.001

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