Enhanced O-linked Glcnacylation in Crohn's disease promotes intestinal inflammation

BACKGROUND: Treatment of Crohn's disease (CD) remains to be a challenge due to limited insights for its pathogenesis. We aimed to determine the role of O-Linked β-N-acetylglucosamine (O-GlcNAc) in the development of CD and evaluate therapeutic effects of O-GlcNAc inhibitors on CD. METHODS: O-Gl...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Qian-Hui, Wang, Yi-Shu, Liu, Guolong, Zhou, Hong-Lan, Jian, Yong-Ping, Liu, Ming-Di, Zhang, Dan, Ding, Qiang, Zhao, Rui-Xun, Chen, Jian-Feng, Li, Yi-Ning, Liang, Jiyong, Li, Yu-Lin, Quan, Cheng-Shi, Xu, Zhi-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047186/
https://www.ncbi.nlm.nih.gov/pubmed/32114385
http://dx.doi.org/10.1016/j.ebiom.2020.102693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047186/
https://www.ncbi.nlm.nih.gov/pubmed/32114385
http://dx.doi.org/10.1016/j.ebiom.2020.102693

Ejemplares similares