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Enhanced O-linked Glcnacylation in Crohn's disease promotes intestinal inflammation

BACKGROUND: Treatment of Crohn's disease (CD) remains to be a challenge due to limited insights for its pathogenesis. We aimed to determine the role of O-Linked β-N-acetylglucosamine (O-GlcNAc) in the development of CD and evaluate therapeutic effects of O-GlcNAc inhibitors on CD. METHODS: O-Gl...

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Detalles Bibliográficos
Autores principales:	Sun, Qian-Hui, Wang, Yi-Shu, Liu, Guolong, Zhou, Hong-Lan, Jian, Yong-Ping, Liu, Ming-Di, Zhang, Dan, Ding, Qiang, Zhao, Rui-Xun, Chen, Jian-Feng, Li, Yi-Ning, Liang, Jiyong, Li, Yu-Lin, Quan, Cheng-Shi, Xu, Zhi-Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047186/ https://www.ncbi.nlm.nih.gov/pubmed/32114385 http://dx.doi.org/10.1016/j.ebiom.2020.102693

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