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Large Sample Size Fallacy in Trials About Antipsychotics for Neuropsychiatric Symptoms in Dementia

BACKGROUND: A typical antipsychotics for neuropsychiatric symptoms in dementia have been tested in much larger trials than the older conventional drugs. The advantage of larger sample sizes is that negative findings become less likely and the effect estimates more precise. However, as sample sizes i...

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Detalles Bibliográficos
Autores principales: Hulshof, Tessa A., Zuidema, Sytse U., Janus, Sarah I. M., Luijendijk, Hendrika J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047221/
https://www.ncbi.nlm.nih.gov/pubmed/32153391
http://dx.doi.org/10.3389/fphar.2019.01701