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Sensing Living Bacteria in Vivo Using d-Alanine-Derived (11)C Radiotracers

[Image: see text] Incorporation of d-amino acids into peptidoglycan is a unique metabolic feature of bacteria. Since d-amino acids are not metabolic substrates in most mammalian tissues, this difference can be exploited to detect living bacteria in vivo. Given the prevalence of d-alanine in peptidog...

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Detalles Bibliográficos
Autores principales: Parker, Matthew F. L., Luu, Justin M., Schulte, Brailee, Huynh, Tony L., Stewart, Megan N., Sriram, Renuka, Yu, Michelle A., Jivan, Salma, Turnbaugh, Peter J., Flavell, Robert R., Rosenberg, Oren S., Ohliger, Michael A., Wilson, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047270/
https://www.ncbi.nlm.nih.gov/pubmed/32123733
http://dx.doi.org/10.1021/acscentsci.9b00743