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Demeclocycline Reduces the Growth of Human Brain Tumor-Initiating Cells: Direct Activity and Through Monocytes

Myeloid cells that infiltrate into brain tumors are deactivated or exploited by the tumor cells. We previously demonstrated that compromised microglia, monocytes, and macrophages in malignant gliomas could be reactivated by amphotericin-B to contain the growth of brain tumorinitiating cells (BTICs)....

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Detalles Bibliográficos
Autores principales: Sarkar, Susobhan, Li, Yibo, Mirzaei, Reza, Rawji, Khalil S., Poon, Candice C., Wang, Jianxiong, Kumar, Mehul, Bose, Pinaki, Yong, V. Wee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047330/
https://www.ncbi.nlm.nih.gov/pubmed/32153581
http://dx.doi.org/10.3389/fimmu.2020.00272