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Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

Selective serotonin reuptake inhibitors (SSRIs) are frequently used to treat depression during pregnancy. Various concerns have been raised about the possible effects of these drugs on fetal development. Current developmental neurotoxicity (DNT) testing conducted in rodents is expensive, time-consum...

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Detalles Bibliográficos
Autores principales: Zhong, Xiali, Harris, Georgina, Smirnova, Lena, Zufferey, Valentin, Sá, Rita de Cássia da Silveira e, Baldino Russo, Fabiele, Baleeiro Beltrao Braga, Patricia Cristina, Chesnut, Megan, Zurich, Marie-Gabrielle, Hogberg, Helena T., Hartung, Thomas, Pamies, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047331/
https://www.ncbi.nlm.nih.gov/pubmed/32153365
http://dx.doi.org/10.3389/fncel.2020.00025