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Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model
Selective serotonin reuptake inhibitors (SSRIs) are frequently used to treat depression during pregnancy. Various concerns have been raised about the possible effects of these drugs on fetal development. Current developmental neurotoxicity (DNT) testing conducted in rodents is expensive, time-consum...
Autores principales: | Zhong, Xiali, Harris, Georgina, Smirnova, Lena, Zufferey, Valentin, Sá, Rita de Cássia da Silveira e, Baldino Russo, Fabiele, Baleeiro Beltrao Braga, Patricia Cristina, Chesnut, Megan, Zurich, Marie-Gabrielle, Hogberg, Helena T., Hartung, Thomas, Pamies, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047331/ https://www.ncbi.nlm.nih.gov/pubmed/32153365 http://dx.doi.org/10.3389/fncel.2020.00025 |
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