IGFBP5 increases cell invasion and inhibits cell proliferation by EMT and Akt signaling pathway in Glioblastoma multiforme cells

BACKGROUND: Recurrence of Glioblastoma multiforme (GBM) seems to be the rule despite combination therapies. Cell invasion and cell proliferation are major reasons for recurrence of GBM. And insulin-like growth factor binding protein 5 (IGFBP5) is the most conserved of the IGFBPs and is frequently dy...

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Detalles Bibliográficos
Autores principales: Dong, Chengyuan, Zhang, Junwen, Fang, Sheng, Liu, Fusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047354/
https://www.ncbi.nlm.nih.gov/pubmed/32127912
http://dx.doi.org/10.1186/s13008-020-00061-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047354/
https://www.ncbi.nlm.nih.gov/pubmed/32127912
http://dx.doi.org/10.1186/s13008-020-00061-6

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