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Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility

BACKGROUND: Zebrafish can faithfully regenerate injured fins through the formation of a blastema, a mass of proliferative cells that can grow and develop into the lost body part. After amputation, various cell types contribute to blastema formation, where each cell type retains fate restriction and...

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Detalles Bibliográficos
Autores principales: Lee, Hyung Joo, Hou, Yiran, Chen, Yujie, Dailey, Zea Z., Riddihough, Aiyana, Jang, Hyo Sik, Wang, Ting, Johnson, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047409/
https://www.ncbi.nlm.nih.gov/pubmed/32106888
http://dx.doi.org/10.1186/s13059-020-1948-0