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METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST

BACKGROUND: N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC. METHODS: Expression level of METTL14 was extracted from pu...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Zhang, Sen, He, Changyu, Xue, Pei, Zhang, Luyang, He, Zirui, Zang, Lu, Feng, Bo, Sun, Jing, Zheng, Minhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047419/
https://www.ncbi.nlm.nih.gov/pubmed/32111213
http://dx.doi.org/10.1186/s12943-020-1146-4