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Enhancing the Signaling of GPCRs via Orthosteric Ions

[Image: see text] G protein-coupled receptors play essential roles in cellular processes such as neuronal signaling, vision, olfaction, tasting, and metabolism. As GPCRs are the most important drug targets, understanding their interactions with ligands is of utmost importance for discovering related...

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Detalles Bibliográficos
Autores principales: Chan, H. C. Stephen, Xu, Yueming, Tan, Liang, Vogel, Horst, Cheng, Jianjun, Wu, Dong, Yuan, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047428/
https://www.ncbi.nlm.nih.gov/pubmed/32123746
http://dx.doi.org/10.1021/acscentsci.9b01247