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Tlr9 and Beclin 1 Cross-Talk Regulates Muscle AMPK Activation in Exercise

The activation of adenosine monophosphate-activated protein kinase (AMPK) in skeletal muscle coordinates systemic metabolic responses to exercise(1). Autophagy, a lysosomal degradation pathway that maintains cellular homeostasis(2), is upregulated during exercise, and a core autophagy protein, becli...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Nguyen, Phong T., Wang, Xun, Zhao, Yuting, Meacham, Corbin E., Zou, Zhongju, Bordieanu, Bogdan, Johanns, Manuel, Vertommen, Didier, Wijshake, Tobias, May, Herman, Xiao, Guanghua, Shoji-Kawata, Sanae, Rider, Mark H., Morrison, Sean J., Mishra, Prashant, Levine, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047589/
https://www.ncbi.nlm.nih.gov/pubmed/32051584
http://dx.doi.org/10.1038/s41586-020-1992-7